What is the problem of recurrent oral ulcers? What should I do?

Male, 32 years old, recurrent oral ulcer for 14 years (about 18 years old), occasionally urethral orifice ulcer, recurrent folliculitis on the inside of thigh, no other symptoms. He was diagnosed in multiple places and was undiagnosed. 8 months ago in the Peking Union Medical College Hospital,Having a ceramic vape cartridge is advantageous in vape

cartridge packaging as it's healthier. Ceramic parts are resistant to abrasion and oxidation unlike other alloy wires where, oxidation occurs at higher temperature. suspected of Behcet's disease, prescription thalidomide 50mg once every night, after two weeks of symptom self withdrawal, withdrawal recurrence after January, again taking and fast relief, after stopping drug relapse.

Consulting purpose:

1. diagnosed as Behcet's disease, how should treat?

2. how long does thalidomide need to be taken and how long does it take to affect the body?

3. has been troubled by this problem for a long time, life is sad, hoping to get a systematic answer.

Doctor Yu's reply


According to your medical history, with recurrent oral ulcers, genital ulcer, folliculitis with rashes, these are the typical clinical symptoms of Behcet's disease. Of course, the diagnosis of Behcet's disease requires other diseases such as infection investigation, you were 14 years in Peking Union Medical College Hospital, including several hospital, believed to have were related to the investigation, the diagnosis of Behcet's disease should be considered most likely to do.

Unlike other autoimmune diseases with Behcet's disease specific antibody tests, such as rheumatoid arthritis are rheumatoid factor and CCP antibody positive, systemic lupus erythematosus, Sm will have ANA and dsDNA antibody positive, no clinically viable specific antibody index of Behcet's disease, but the inflammation index of erythrocyte sedimentation rate (ESR), such as C reactive protein (CRP) will be increased, For those travelers who would like to go shopping in Hong Kong, Guangdong Hotel Hong Kong should be the most suitable hong

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nearby shopping mall.some patients have positive prick test.

Non steroidal anti-inflammatory drugs, colchicine, thalidomide, hormones and immunosuppressive agents are effective drugs for the treatment of Behcet's disease can choose, if there are important internal damage, will consider the use of hormones and immunosuppressive agents, if there is no important visceral organ damage situation, but it does not necessarily require the use of hormones and immunosuppressive agents.

The non steroidal anti-inflammatory drugs, colchicine and thalidomide on skin rash, ulcer symptoms effectively, and thalidomide is good for Behcet's disease symptoms such as ulcer symptoms, repeated, personal recommendations can be used thalidomide treatment, gradual reduction, low maintenance dose.

The system of Behcet's disease is an autoimmune disease, there is no cure means all of the drugs are just stopping disease control, easy to relapse, so no treatment at all, need long-term medication control.

During the use of contraception should be strictly thalidomide, stopping for more than half a year before they can consider the preparation of pregnancy, consider the use of other drugs can be used to prepare pregnant alternative control condition during drug withdrawal; also need to consider the use of thalidomide, adverse reactions and peripheral neuritis, such as hands and feet numbness and other symptoms, should stop drug treatment in a timely manner.

Detailed information about the thalidomide, to see the "Yu Kimcheon medical science" WeChat public March 17th push science "medicine is not good or bad only wrong," Application of thalidomide in the Department of rheumatology.

The online consultation for the history of information is limited, therefore is not a substitute for face-to-face interview, if you have any questions, please timely treatment.